Police are keen to trace James Bould, 34, who went missing from his place of work in Dewsbury town centre at 8am this morning.
Mr Bould has an existing medical condition and there are immediate concerns for his welfare.
He was last seen wearing a red t-shirt with blue stripes on the sleeve, navy blue jogging pants with royal blue stripes down the sides, a green parka coat and a burgundy red bobble hat.
He is 5ft 8ins tall and of average build.
He has pale skin with a stubbly beard, blue eyes and auburn hair which is short at the back and has longer sweeping fringe.
Mr Bould may be travelling by public transport as he does not own a vehicle and there is a possibility that he has gone to Bradford, though his whereabouts are not known.
If anyone has any information or sees Mr Bould, please contact Kirklees CID on 101.